These recommendations are based on available evidence, such as it exists they also rely heavily on the opinion of the Work Group members and are graded accordingly. Thus, the Work Group has generated a set of guideline recommendations to provide guidance to practitioners on the clinical aspects of nutrition management while at the same time recognizing the limited evidence that exists. In addition, the quality of evidence in pediatric nephrology studies related to the issues addressed in these guidelines was frequently low due to small sample size, the lack of randomized controlled trials, and the lack of information for both short- and long-term clinical outcomes. One of the challenges for the Work Group in revising the 2000 K/DOQI Pediatric Nutrition Guidelines was the remarkable lack of published data available for the topic of nutrition in children with all stages of CKD. 40th Anniversary Special Collection: Kidney Transplantation.40th Anniversary Special Collection: CKD.
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